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1 656 870

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IPC

(21) (22)

Application

4724928/13, 1989-07-27

(22)

Actual filing date

1989-07-27

(45)

Published

1994-09-30

(72)

Inventor

Demchenko В.I.Domrachev N.V.Кrymov А.Р.Gireva N.N.Мart'Janova V.N.Navtsenja L.G.Naumova G.А.Тjuljaev I.I.Vajsman Е.М.

METHOD OF 11β-HYDROXYSTEROID SYNTHESIS Russian patent published in 1994 - IPC

Abstract SU 1656870 A1

FIELD: steroid synthesis, biotechnology. SUBSTANCE: synthesis of 11b-hydroxysteroids is carried out by microbiological hydrolysis of 11b-acylhydroxysteroids by culture Corynebacterium mediolanum (strain VKPM B-964). Hydrolysis is carried out at 33 C with substrate loading 0.3-10 g/l depending on the substrate structure. Hydrolysis time is 6-48 h. EFFECT: intensification and acceleration of process owing to utilization of 11b-acylhydroxysteroids containing C₂-C₇-acyl residues.

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SU 1 656 870 A1

Authors

Demchenko В.I.

Domrachev N.V.

Кrymov А.Р.

Gireva N.N.

Мart'Janova V.N.

Navtsenja L.G.

Naumova G.А.

Тjuljaev I.I.

Vajsman Е.М.

Dates

1994-09-30—Published

1989-07-27—Filed