FIELD: steroid compounds, more particularly (22RS-16α; 17α-butylidenedioxy-11β, 21-dihydroxypregna-1,4-diene-3.20-dione 11,21-diacetate as an intermediate product in the synthesis of budeconide. SUBSTANCE: the semifinished product is synthesized by acetalization of 16α-oxyprednisolone 11.21-diacetate with butyric aldehyde in a CH2Cl2 solution in the presence of a HClO4 catalyst. The yield 96.5%, mp 118-128 C after decrystallization 150-160 C; [α]
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Authors
Dates
1994-09-30—Published
1989-07-27—Filed