METHOD FOR DIFFERENTIAL DIAGNOSIS OF VERSIONS OF ATOPIC BRONCHIAL ASTHMA IN CHILDREN Russian patent published in 1994 - IPC

FIELD: medicine. SUBSTANCE: method involves scarifying the skin in right and left forearms of the patient and, and after taking diagnostic samples for causative allergen and control fluid thereon, fixing sterile object glasses and chambers with physiological solution, respectively, on upper and lower portions of scarification scratches. The glasses and the content of chambers are changed after 1.5-6.23-24 h then concentrations of histamine and prostoglandine E are assessed, glasses in chambers are fixed and colored by Romanovsky method, and the percentage of cell subpopulations is determined. Next steps are calculating coefficients K₁, K₂, K₃, K₄ by formulas K₁= histamine control/histamine experiment (after 1.6 h), K₂=PGE₂ experiment/PGE₂ control (after 6 h), K₃ = % of granulocytes experiment/ % of granylocytes control (after 6 h), K₄ = % of macrophages experiment/ % of macrophages control (after 24 h) and at the value of K₁≥ 2, K₂≥ 10, K₃≥ 1,5, K₄≅ 0,85 the progress of atopic bronchial asthma with late and early phases is diagnosed while at a relation of K₁<2, K₂<10, K₃<1,5, K₄>0,85 the version is diagnosed with the early phase alone. EFFECT: higher accuracy of diagnosis.