FIELD: organic chemistry. SUBSTANCE: method involves the use of derivatives of oxalylamino acids of the formula (I) where R1 and R2 are similar or different and mean C1-C3-alkyls, Na or K; R1 - means hydrogen or methyl; R2 - means hydrogen, C1-C3-alkyl, benzyl or thiomethyl, or R1 and R2 together form alkylene chain. Compounds showed as excellent inhibitors of proline- and lysine hydroxylase, fibro- or immune depressants, curative agents at collagen and collagen-like substances metabolism disorder. EFFECT: enhanced effectiveness of inhibitors indicated above. 1 tbl
Authors
Dates
1994-12-30—Published
1991-05-10—Filed