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2 027 696

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C1

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IPC

(21) (22)

Application

5027212/04, 1992-02-17

(22)

Actual filing date

1992-02-17

(45)

Published

1995-01-27

(72)

Inventor

Oganesjan Eh.T.Ivchenko A.V.Kul'Bekov E.F.

(73)

Holder

Pjatigorskij Farmatsevticheskij Institut

CYCLOHEXANEDIONE DERIVATIVES SHOWING CHOLAGOGUE ACTIVITY Russian patent published in 1995 - IPC

Abstract RU 2027696 C1

FIELD: organic chemistry. SUBSTANCE: product - derivatives of cyclohexanedione: a) 5,5-dimethyl-2-(methoxybenzylidene)-cyclohexanedione-1,3, empirical formula is БФ С16H18O3, yield is 81%, m. p. is 166-168 C; b) 5,5-dimethyl-2-(nitrobenzylidene)-cyclohexanedione-1,3, empirical formula is C15H15NO4, yield is 79%, m. p. is 149-150 C. Reagent 1: 5,5-dimethylcyclohexanedione-1,3. Reagent 2: 2-methoxy- or 3-nitrobenzaldehyde. Reaction conditions: dissolving of reagent 1 in ethanol and addition of 15% solution of sodium hydroxide. Synthesized compounds were used in medicine as cholagogue agents. EFFECT: improved method of synthesis, increased yield of products. 1 tbl

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RU 2 027 696 C1

Authors

Oganesjan Eh.T.

Ivchenko A.V.

Kul'Bekov E.F.

Dates

1995-01-27—Published

1992-02-17—Filed

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