FIELD: organic chemistry. SUBSTANCE: product: 11b-acyloxy-17a-hydroperoxy-16a-methylpregnanes of the formula (I) (image), where a) R1 and R2 - acetoxy; X - F; b) R1 and R2 - acetoxy; X - H; c) R1 - acetoxy; R2 - propionyloxy; X - F; d) R1 - acetoxy; R2 - heptanoyloxy; X - F; e) R1 and R2 - propionyloxy; X - F. Reagent 1: corresponding Δ16Cl-20-ketopregnanes. Reagent 2: methylmagnesium bromide in the presence of CuCl in the medium of acetonitrile and a mixture of toluene/benzene at (-15)-(-30) C. Reagent 3: NH4Cl. Synthesized steroids were used in medicine. EFFECT: improved method of synthesis.
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