N-ALKYL DERIVATIVES OF ANTIBIOTICS OR THEIR PHARMACEUTICALLY AVAILABLE SALTS HAVING ANTIFUNGOUS ACTIVITY AS INTERMEDIATE COMPOUND IN SYNTHESIS OF N-ALKYL DERIVATIVES OF ANTIBIOTICS, METHOD FOR PRODUCTION OF N-ALKYL DERIVATIVES OF ANTIBIOTICS OR THEIR PHARMACEUTICALLY AVAILABLE SALTS Russian patent published in 1995 - IPC

FIELD: production of antibiotics. SUBSTANCE: desired products have common formula I where R₁ is hydrogen or methyl (in this case D-alanine is prepared), R₂ is hydrogen or β-D-xylosyle; Y-group is where R₃-R₅ are the same or different C₁-C₅-alkyls. Novel compound having formula II is used as reagent 1. Aldehyde having 1-5 carbon atoms is used as reagent 2. Reaction is carried out at pH 8.0-8.5, it is followed by treatment with reduction agent. EFFECT: improves desired product quality, increases efficiency of the method. 4 cl, 2 tbl