THIAZOLE DERIVATIVES Russian patent published in 1995 - IPC

Abstract RU 2048468 C1

FIELD: organic chemistry. SUBSTANCE: product: 2-propionyl-5-(4-nitrophenylthio)-thiazole, yield is 78.7% m. p. is 227-229 C (with decomposition). 2-Propionylthio-5-(4-aminophenylthio)-thiazole, yield is 96.3% m. p. is 185-187 C. 2-Amino-5-(1-methyl-1H-tetrazole-5-yl-thio)-thiazole, yield is 48.5% m. p. is 186-188 C (with decomposition). Synthesized compounds were used for synthesis of pharmacological drugs used for therapy of rheumatism, nephritis, thrombocytopenia. EFFECT: improved method of synthesis. 6 cl

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RU 2 048 468 C1

Authors

Masaaki Matsuo[Jp]

Takasi Ogino[Jp]

Norikhiro Igari[Jp]

Khatiro Seno[Jp]

Kioiti Simomura[Jp]

Dates

1995-11-20Published

1991-11-22Filed