FIELD: biotechnology, enzymology. SUBSTANCE: 1000 U urokinase preparation is dissolved in 7.5-10 ml 1.0-5% solution of ethylenediaminetetraacetic acid disodium salt, to prepared solution 0.05-0.1 g hyaluronic acid is added and heated at 75-85 C for 4-6 hr. Prepared enzyme solution retains the initial activity completely and does not contain active virus forms. Method is used for virus inactivation in an enzyme preparation. EFFECT: improved method of urokinase stability increase. 1 dwg, 1 tbl
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