FIELD: medicine, oncology, pharmacy. SUBSTANCE: proposed antileukosis medicinal preparation contains cytarabine in the liposomal form of the following composition, wt.-%: cytarabine 0.8-0.9; lecithin 8-9; cholesterol 1.2-1.4; sucrose 5.0-5.4; vitamin E 0.004-0.008, and water - up to 100. Effectiveness of cytarabine incorporation into liposomes is 30-45%, mean volume-numerical liposome diameter is 300-600 nm. Proposed preparation can be used in medicine for leukosis treatment. EFFECT: enhanced effectiveness of preparation. 1 tbl
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Authors
Dates
1996-10-27—Published
1992-03-06—Filed