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2 069 692

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(51)

IPC

(21) (22)

Application

93045423/13, 1993-09-23

(22)

Actual filing date

1993-09-23

(45)

Published

1996-11-27

(72)

Inventor

Mazurova I.K.Mikhajlovich V.M.Garaev M.M.Zaikin V.L.

(73)

Holder

Moskovskij Nauchno-Issledovatel'Skij Institut Ehpidemiologii I Mikrobiologii Im.G.N.Gabrichevskogo

STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF SPECIFIC DNA-PROBE USED FOR DIFFERENTIATION OF TOXIGENIC AND NONTOXIGENIC STRAINS OF CORYNEBACTERIUM DIPHTHERIAE AND COMPLEMENARY TO TOX BREHY DETERMINING SYNTHESIS OF DIPHTHERIA TOXIN Russian patent published in 1996 - IPC

Abstract RU 2069692 C1

FIELD: medicine, molecular biology. SUBSTANCE: method involves nucleic acid hybridization. Invention relates to preparing strain Escherichia coli C600 r^-m^- (pSS6 tox B') - a producer of specific DNA-probe used for differentiation of toxigenic and nontoxigenic strains of Corynebacterium diphtheriae. Strain provides high yield of plasmid DNA pSS6 tox B' which is used at DNA-DNA hybridization as specific probe. EFFECT: preparing strain indicated above, high yield of plasmid DNA.

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RU 2 069 692 C1

Authors

Mazurova I.K.

Mikhajlovich V.M.

Garaev M.M.

Zaikin V.L.

Dates

1996-11-27—Published

1993-09-23—Filed