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2 069 693

(13)

(51)

IPC

(21) (22)

Application

93046076/13, 1993-09-23

(22)

Actual filing date

1993-09-23

(45)

Published

1996-11-27

(72)

Inventor

Mazurova I.K.Zaikin V.L.Jankovskij N.K.Zdanovskij A.G.

(73)

Holder

Moskovskij Nauchno-Issledovatel'Skij Institut Ehpidemiologii I Mikrobiologii Im.G.N.Gabrichevskogo

STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF SPECIFIC DNA-PROBE USED FOR DIFFERENTIATION OF TOXIGENIC AND NONTOXIGENIC CORYNEBACTERIUM DIPHTHERIAE AND COMPLEMENTARY TO TOX GENE DETERMINING SYNTHESIS OF DIPHTHERIA TOXIN Russian patent published in 1996 - IPC

Abstract RU 2069693 C1

FIELD: medicine, molecular biology. SUBSTANCE: method involves nucleic acid hybridization. Invention relates to preparing strain Escherichia coli C600 r^-m^- (pABC 124 tox AB') - a producer of specific DNA-probe for differentiation of toxigenic an nontoxigenic strains of Corynebacterium diphtheriae. Strain provides high yield of plasmid DNA pABC 124 tox AB' which is used for DNA-DNA hybridization as specific probe. EFFECT: preparing strain indicated above, high yield of plasmid DNA.

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RU 2 069 693 C1

Authors

Mazurova I.K.

Zaikin V.L.

Jankovskij N.K.

Zdanovskij A.G.

Dates

1996-11-27—Published

1993-09-23—Filed