FIELD: medicine. SUBSTANCE: new compound having six-member cycle is camptotecin derivative of general formula I. The compound is prepared from aminoketone and pyranoindolysine compound by reaction of i.e. closing of the ring. The compound is readily soluble and has excellent antitumor activity and high degree of safety, it can be used as antitumor agent for treatment tumors of various types. Compound of formula I: $$$. EFFECT: improved properties of the hexacyclic compound. 9 cl, 50 ex, 1 tbl
Authors
Dates
1997-01-10—Published
1992-01-15—Filed