3-ARYLCARBONYL-1-AMINOALKYL-1H-INDOLES Russian patent published in 1997 - IPC

Abstract RU 2073670 C1

FIELD: organic chemistry. SUBSTANCE: product: 3-arylcarbonyl-1-aminoalkyl-1H-indoles of the formula where: R2 - H, lower alkyl; R3 - lower alkoxymethylphenyl, tri-lower-alkoxyphenyl, benzyl, lower alkoxystyryl, 1H-imidazole-1-yl/naphthyl, 2-(1-naphthyl)ethynyl, 1-(1,2,3,4-tetrahydronaphthyl), anthryl, phenanthryl or pyrenyl. Reagent 1: 2-R2-substituted 3-R3-carbonyl-1H-indole. Reagent 2: aminoethyl-halide. Reaction condition: in the presence acceptor HCl. Synthesized compounds were used in ophthalmology for glaucoma treatment. EFFECT: improved method of synthesis. 4 cl, 5 tbl

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RU 2 073 670 C1

Authors

S'Juzan Dzhin Vord[Us]

Malkol'M Rajs Bell[Us]

Dates

1997-02-20Published

1992-05-27Filed