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2 077 337

(13)

C1

(51)

IPC

(21) (22)

Application

93052668/13, 1993-11-22

(22)

Actual filing date

1993-11-22

(45)

Published

1997-04-20

(72)

Inventor

Martynenko L.D.Beletskaja S.G.Aleshkin V.A.

(73)

Holder

Nauchno-Proizvodstvennoe Ob"EdinenieKontsern

METHOD OF FIMBRIAL ADHESINE PREPARING Russian patent published in 1997 - IPC

Abstract RU 2077337 C1

FIELD: medicinal biotechnology. SUBSTANCE: method involves culturing microorganism-producer followed by inactivation, separation and mechanical disruption of microbial cells and isolation of fimbrias by precipitation with ammonium sulfate. Before disruption microbial cells were washed off with sodium chloride saturated solution and the isolated fimbrias were subjected for dialysis against phosphate buffer followed by ultrasonic or chemical disruption, gel-filtration and concentration by treatment with polyethylene glycol. Obtained bacterial fimbrial adhesine can be used as diagnostic and prophylaxis preparation. EFFECT: improved method of preparing. 3 tbl

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RU 2 077 337 C1

Authors

Martynenko L.D.

Beletskaja S.G.

Aleshkin V.A.

Dates

1997-04-20—Published

1993-11-22—Filed

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