METHOD OF SYNTHESIS OF 2-SUBSTITUTED 4,6-DIALKOXYPYRIMIDINES, 2-N-BUTYLAMINO-4,6-DIMETHOXYPYRIMIDINE AND A METHOD OF SYNTHESIS OF HALOGEN-DERIVATIVE OF PYRIMIDINE Russian patent published in 1998 - IPC

FIELD: organic chemistry and technology. SUBSTANCE: invention proposes a method of synthesis of 2-substituted 4,6-dialkoxypyrimidines of the formula (I) where R₁ and R₂ - are similar or different (C₁-C₄)-alkyl; R₃-R₄ is -O-; R₄ is -S- or R₄R₅N where R₄ - (C₁-C₄)-alkyl; R₅ - hydrogen, (C₁-C₄)-alkyl or phenyl. Compounds are synthesized by cyclization reaction of cyanoimidate of the formula (II) with hydrogen halogen and pyrimidine halogen-derivative of the formula (III) is formed. The latter is reacted with compound of the formula (IV) M-R₃ where R₃= R₄ is -O- or R₄ is -S-; M - alkaline metal atom, or with alkylamine of the formula (V) and converted to the end compound of the formula (I). Also, 2-N-butylamino-4,6-dimethoxypyrimidine is described. Synthesized compounds are used as semiproducts for synthesis of herbicides. EFFECT: improved method of synthesis. 10 cl, 1 tbl