SIDE CHAIN TAXANES, INTERMEDIATE COMPOUNDS, AND METHODS OR PREPARING, THEREOF Russian patent published in 1999 - IPC

FIELD: medicine. SUBSTANCE: present invention describes side chain taxanes and intermediates thereof and novel compounds of formula III. Oxazoline side taxanes of formula III: R¹ wherein R⁴, is phenyl, alkyl, alkenyl, alkoxy; R³ is H; R⁸ is phenyl, benzyl or furyl; R⁹ and R¹⁴O are H, OH or R¹⁰; R¹¹ and C_3-7 are independently hydrogen, alkyl, alkenyl, R¹⁴-cycloalkyl, phenyl; is hydroxy protecting group, and salts thereof show antitumor activity. EFFECT: improved properties of the title compounds. 81 cl, 86 ex