FIELD: chemical technology. SUBSTANCE: purification is carried out by centrifuge chromatography using solvent mixtures. For purification of 10-deacetylbaccatin and taxoter a mixture of aliphatic hydrocarbon, ester, alcohol and water is used (interphase distribution coefficient is from 0.1 to 10). For purification of 10-deacetylbaccatin-III a mixture of aliphatic ketones and water is used (the above indicated index is 0.1-10). Invention relates to also taxoter trihydrate. EFFECT: decreased solvents consumption, improved phase separation and stability. 10 cl, 3 ex
| Title |
Year |
Author |
Number |
| TAXOIDS, METHODS OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS AND PHARMACEUTICAL COMPOSITION |
1993 |
- Ehrve Bushar
- Zhan-Dominik Burza
- Alen Kommerson
|
RU2139864C1 |
| METHOD FOR PRODUCTION OF DERIVATIVES OF TAXANE |
1993 |
- Ehli Fuke[Fr]
- Zhan-Manjuel' Ma[Fr]
|
RU2103266C1 |
| DERIVATIVES OF TAXANE |
1993 |
- Deni Zhan-Noel'
- Grin Ehndrju
- Kanazava Alis
|
RU2188198C2 |
| ACID ANHYDRIDES, METHOD OF PREPARATION THEREOF, METHODS OF PREPARATION THEREOF, METHODS OF PREPARATION OF TAXOL OR TAXOTERAN |
1993 |
|
RU2104274C1 |
| METHOD OF SYNTHESIS OF TAXANE DERIVATIVES AND INTERMEDIATE COMPOUNDS OF SYNTHESIS |
1993 |
- Zhan-Noel' Deni
- Ehndrju Grin
- Alis Kanazava
|
RU2118958C1 |
| METHOD FOR PRODUCTION OF TAXANE DERIVATIVES AND INTERMEDIATES BY THEIR PRODUCTION |
1993 |
- Alen Kommerson
- Ehrik Did'E
- Ehli Fuke
|
RU2116302C1 |
| METHOD OF SYNTHESIS OF BACCATIN-III AND 10-DEACETYLBACCATIN-III ESTERS, ACTIVATED ACIDS AND THEIR DERIVATIVES |
1993 |
- Zhan-Noehl' Deni
- Ehndrju Grin
- Zhan-Manjuel' Mas
|
RU2123493C1 |
| METHOD FOR PRODUCTION OF TAXANE DERIVATIVES |
1993 |
- Zhan-Manjuel' Mas
- Viv'Jan Massono
|
RU2116303C1 |
| TAXOIDS, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION BASED ON THESE COMPOUNDS |
1995 |
- Bushar Ehrve
- Burza Zhan-Dominik
- Kommerson Alen
- Terr'E Korinn
- Zjukko Martin
|
RU2153496C2 |
| N-BENZYL-β-PHENYLISOSERIN-(2R,3S), METHOD FOR ITS PRODUCTION AND METHOD OF PRODUCTION OF ESTER OF b-PHENYLISOSERIN-(2R,3S) |
1991 |
- Zhan-P'Er Djushesn[Fr]
- Mishel' Mjul'Ozer[Fr]
|
RU2074172C1 |
