FIELD: medicine, pharmacy. SUBSTANCE: invention relates to rapamycin that is a macrocyclic triene antibiotic produced by microorganism Streptomyces hygroscopicus. Compounds are used in pharmaceutical compositions for stimulation of immunodepression and therapy of graft rejections at transplantation, autoimmune diseases, inflammatory processes, solid tumors and fungal infections. EFFECT: enhanced effectiveness of a composition. 37 cl
| Title |
Year |
Author |
Number |
| C-22 STABILIZED DERIVATIVES OF RAPAMYCIN, METHOD OF IMMUNO- -SUPPRESSION INDUCING, METHOD OF TREATMENT AND PROPHYLAXIS OF TRANSPLANT REJECTION OR HOMOLOGOUS DISEASE, METHOD OF TREATMENT OR PROPHYLAXIS OF HYPERPROLIFERATIVE VASCULAR DISORDER |
1994 |
|
RU2152946C1 |
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1996 |
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- M'Jusho Richard Ehrik
- Bravo Bajron Abel'
- Kang Jang Khi
|
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1991 |
- Majkl Sotirios Malamas[Gr]
|
RU2110518C1 |
| RAPAMYCIN HYDROXYESTERS, METHOD OF THEIR SYNTHESIS AND METHODS OF TREATMENT |
1995 |
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|
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1995 |
- Amedeo Arturo Failli
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- Oleg Igorevich Blejman
|
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| DERIVATIVES OF [([2- (AMINO -3,4-DIOXO -1-CYCLOBUTENE -1-YL)AMINO]ALKYL)] ACIDS |
1992 |
- Uil'Jam Alvin Kinni[Us]
- Dinna Kolett Garrison[Us]
|
RU2039035C1 |
| RAPAMYCIN ESTERS |
1996 |
|
RU2160739C2 |
| METHOD OF OBTAINING SUBSTITUTED 1,3,4,9-TETRAHYDROPYRANO/3,4-INDOLE-1-ACETIC/ ACIDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF |
0 |
- Alan Khovard Kats
- Kristofer Aleksandr Demerson
- Lesli Dzhordzh Khamber
|
SU1531856A3 |
|
0 |
- Kurt Villi Ledig
- Devid Richard Kherbst
|
SU512713A1 |
| DERIVATIVES OF THIAZOLIDINEDIONE OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, A METHOD OF TREATMENT OF MAMMALIAN WITH HYPERGLYCAEMIA, A PHARMACEUTICAL COMPOSITION |
1995 |
- Dzhej Ehdvard Robel'
- Zenan Li
- Ehrlin Dzhoan Ditrikh
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RU2126395C1 |
