FIELD: medicine. SUBSTANCE: described are new rapamycin esters of general formula I: 
wherein R1 is 
; R2 is hydrogen or is as defined above for R1, and n is 8-200. Compounds are useful as immunosuppressive antiinflammatory, antifungal, antiproliferative and antitumor agent. EFFECT: improved properties of the title compound. 7 cl, 5 ex
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Year |
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| C-22 STABILIZED DERIVATIVES OF RAPAMYCIN, METHOD OF IMMUNO- -SUPPRESSION INDUCING, METHOD OF TREATMENT AND PROPHYLAXIS OF TRANSPLANT REJECTION OR HOMOLOGOUS DISEASE, METHOD OF TREATMENT OR PROPHYLAXIS OF HYPERPROLIFERATIVE VASCULAR DISORDER |
1994 |
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