FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention describes novel compounds, namely, aminomethyl-2,3,8,9-tetrahydro-7H-1,4-dioxino[2,3-e] -indole-8-one compounds of the formula (I) 
where R1 and R2 mean independently hydrogen atom; or R1 and R2 taken in common mean benzylidene optionally substituted with radical R3 determine below; or R1 and R2 taken in common with carbon atom to which they are bound form carbonyl fragment; R3 means hydrogen, halogen atom, trifluoromethyl-group, trifluoromethoxy-group, alkyl with 1-6 carbon atoms, alkoxy-group with 1-6 carbon atoms, amino-group, mono- or dialkylamino-group where each alkyl group has 1-6 carbon atoms, alkaneamido-group with 2-6 carbon atoms; R4 means hydrogen atom or alkyl with 1-6 carbon atoms; m = 0, 1; n = 0, 1, 2, 3, 4, 5 or 6; Z means hydrogen atom, hydroxy-group, alkyl with 1-6 carbon atoms, alkenyl with 2-6 carbon atoms, alkynyl with 1-6 carbon atoms, cycloalkyl with 3-8 carbon atoms, polycyclic alkyl with 7-15 carbon atoms, phenyl optionally substituted with R3 determined above, phenoxy-group optionally substituted with R3 determined above, naphthyl optionally substituted with radical R3 determined above, naphthyloxy optionally substituted with radical R3 determined above, heteroaryl or heteroaryloxy-group where heterocyclic ring of heteroaryl or heteroaryloxy-group is taken among thiophene, furan, pyridine, indole, quinoline and heterocyclic ring is the optionally substituted radical R3 determined above; or their pharmaceutically acceptable salts. Invention describes also method of treatment of patients. New compounds can be used for treatment of patients with disorders of dopaminergic system. EFFECT: new compounds indicated above, valuable medicinal properties of compounds. 42 cl, 46 ex
