FIELD: pharmacy. SUBSTANCE: invention relates to a solid pharmaceutical dosing form that provides the slow release of drug. The form is obtained by direct pressing cross-linked amylose of different cross-linking degree, α--amylase and a pharmaceutical agent. Cross-linked amylose ensures to provide the gradual drug release and α--amylase ensures to modulate time of release. Amount of α--amylase is 100 or less enzymatic units. EFFECT: improved quality and properties of the form. 5 cl, 5 dwg, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| CROSS-LINKED HIGH-AMYLOSE STARCH FOR USING IN PHARMACEUTICAL COMPOSITION WITH SUSTAINED-RELEASING AND METHOD FOR ITS PREPARING | 2001 |
|
RU2274443C2 |
| TWO-LAYER COMPOSITION FOR CONTINUOUS RELEASE OF ACETAMINOPHEN AND TRAMADOL | 2008 |
|
RU2469718C2 |
| COMPOSED TRAMADOLE OF PROLONGED RELEASE WITH 24- HOUR ACTION | 2003 |
|
RU2328275C2 |
| COMPOSITIONS WITH CONTROLLED LIBERATION | 2003 |
|
RU2333745C2 |
| CROSS-LINKED PROTEIN CRYSTAL WITH CONTROLLED DISSOLVING | 1998 |
|
RU2241746C2 |
| CROSS-LINKED LIPASE CRYSTALS, COMPOSITION BASED THEREON AND METHOD FOR MAKING THEREOF | 1998 |
|
RU2380415C2 |
| HYBRID INDUCED RELEASING COVER | 2008 |
|
RU2478303C2 |
| SYSTEM FOR PROLONGED RELEASE OF SOLUBLE DRUG | 2002 |
|
RU2322263C2 |
| CROSS-LINKED COPOLYMERS BASED ON POLYCARBOXYLIC POLYMERS, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS COMPRISING CROSS-LINKED COPOLYMERS | 1997 |
|
RU2194055C2 |
| PHARMACEUTICAL FORM FOR DRUG DELIVERY TO THE COLON | 2007 |
|
RU2646825C2 |
