FIELD: veterinary science, virology. SUBSTANCE: invention relates to preparing diagnostic antigens. Foot and mouth disease virus type A, strain N 1707 "Armenia-98", is cultured on monolayer of cells VNK-21 or PSGK-30. Obtained virus is concentrated with polyethylene glycol, purified with chloroform and inactivated with aminoethylethyleneimine. An antigen is dried by lyophilization method if an antigen has no the residual virulence and activity in RSL 1:9 and above. Stabilizing agents based on sucrose and gelatin are used. EFFECT: increased activity and specificity of the preparation. 2 dwg, 4 tbl, 2 ex
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Authors
Dates
1999-11-10—Published
1999-03-15—Filed