FIELD: virology, biotechnology. SUBSTANCE: foot- and-mouth virus of type O, strain = 1734/Primorsky/2000 is cultured in monolayer of cells VNK-21, PSGK-30 or IB-RS-2. Prepared virus particles are purified from inert impurities with chloroform, concentrated with polyethylene glycol and inactivated with aminoethylethyleneimine. In absence of residual virulence and activity in PCK 1:8 and above antigen is dried by method of lyophilization using stabilizing agents based on sucrose and gelatin. EFFECT: enhanced activity and specificity of preparation. 7 cl, 4 tbl, 2 dwg, 3 ex
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