DERIVATIVES OF LIPOPEPTIDE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF Russian patent published in 1999 - IPC

Abstract RU 2141970 C1

FIELD: organic chemistry, peptides, pharmacy. SUBSTANCE: invention describes new lipopeptide derivatives of the formula (I) where R¹ means OH or NH₂; R² means linear or branched, saturated or unsaturated, aliphatic C₈-C₂₂-acyl residue that can be broken by phenyl groups or oxygen atom, and their pharmaceutically acceptable salts. They are derivatives of antibiotics of lipopeptide complex A1437. Invention describes also a method of their synthesis and a pharmaceutical composition based on compounds of the formula (I). EFFECT: improved method of synthesis, new lipopeptides. 7 cl, 4 tbl, 72 ex

Similar patents RU2141970C1

Title	Year	Author	Number
METALLOCENES WITH BENZOFUSED INDENYL DERIVATIVES, METHOD OF THEIR SYNTHESIS, METHOD OF OLEFIN POLYMER PRODUCING AND CATALYST FOR OLEFIN POLYMERIZATION	1992	Jurgen Rormann[De] Fol'Ker Dolle[De] Andreas Vinter[De] Frank Kjuber[De]	RU2098423C1
METHOD OF SYNTHESIS OF 2-FORMYLBENZYLPHOSPHONIC ACID DERIVATIVES	1990	Anushirvan Pejman[De] Ojgen Ul'Mann[De] Irvin Vinkler[De] Mattias Khelsberg[De] Kristof Majkhsner[De]	RU2039063C1
METALLOCENES WITH ARYL-SUBSTITUTED INDENYL DERIVATIVES, METHOD OF SYNTHESIS OF OLEFIN POLYMERS AND CATALYST FOR OLEFINS POLYMERIZATION	1993	Frank Kjuber Bernd Bakhmann Val'Ter Shpalek Andreas Vinter Jurgen Rormann	RU2118961C1
SUBSTITUTED DERIVATIVES OF CYCLOHEXANE	1993	Khorst Khemmerle Peter Shindler Andreas Kherling	RU2126378C1
BRIDGE CHIRAL METALLOCENES AND A METHOD OF THEIR SYNTHESIS (VARIANTS)	1992	Jurgen Rormann[De]	RU2081876C1
HETEROCYCLIC DERIVATIVES OF CARBOXYLIC ACID AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS	1994	Klaus Vejdmann Karl-Gejnts Baringkhauz Georg Tshank Martin Bikel'	RU2145959C1
METHOD OF SYNTHESIS OF 2-SUBSTITUTED 4-(3-TERT -BUTYL-4-HYDROXYPHENYL)THIAZOLES	1990	Verner Torvart[De] Rudol'F Shlejerbakh[De] Robert Bertlett[Us] Klaus Ul'Rikh Vajtmann[De]	RU2017739C1
METHOD FOR PRODUCTION OF POLYOLEFINS	1992	Val'Ter Shpalek[De] Jurgen Rormann[De] Martin Antberg[De]	RU2078771C1
DERIVATIVES OF GUANIDINEALKYL-1,1-BIS-PHOSPHONIC ACID, METHOD OF THEIR SYNTHESIS, DRUG AND METHOD OF ITS SYNTHESIS	1992	Khans-Jokhen Lang Kristof Nojmann Deni Karn'Jato Ann-Mari Mura Rioishi Sato Masakazu Kato	RU2124519C1
DERIVATIVES OF CYCLOHEXANE CARBOXYLIC ACID, MIXTURE OF THEIR ISOMERS OR SEPARATE ISOMERS AND PHYSIOLOGICALLY TOLERANT SALTS, PHARMACEUTICAL COMPOSITION	1995	Khorst Khemmerle Gerrit Shubert Khans-Erg Burger Andreas Kherling Suad Ehffendich	RU2140416C1

RU 2 141 970 C1

Authors

Rudol'F Lattrel'

Teodor Vol'Mann

Khol'Ger Val'Majer

Peter Khammann

Diter Isert

Dates

1999-11-27—Published

1995-03-29—Filed