FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes novel 2-heteroaryl-5,11-dihydro-6H-dipyrido[3,2-b: 2',3'-e][1,4]- -diazepine-6-ones, their pharmaceutically acceptable salts, a pharmaceutical composition showing inhibitory activity with respect to HIV-1 reverse transcriptase of the general formula (I) 
where R1, R2 and Ar have values given in p. 1 of the invention claim and their pharmaceutically acceptable salts. Compounds of the formula (I) and their salts can be as an active substance of the pharmaceutical composition showing an inhibitory activity with respect to HIV-1 reverse transcriptase. EFFECT: new compounds indicated above, valuable inhibitory properties. 5 cl, 1 tbl
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