OXAZOLIDINONES, THEIR SALTS, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL PREPARATION AND METHOD OF ITS PREPARING Russian patent published in 2000 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to new derivatives of oxazolidinones of the general formula (I) given in description and their salts also. Method of synthesis of the compound of the general formula (I) involves the conversion of the compound of the formula (I) where R₁ means phenyl substituted with CN-group to compounds of the formula (I) where R₂ means phenyl substituted with amidine group; Y has values given in p. 1 of the invention claim. Pharmaceutical preparation showing inhibitory activity of fibrinogen binding containing compounds of the formula (I) and pharmaceutically acceptable carrier and a method of its preparing. These compounds can be used for treatment of patients with thrombosis, myocardium infarction, inflammations, tumors. EFFECT: improved method of synthesis and preparing, valuable pharmacological properties. 5 cl, 25 ex