FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to spiro-azabicyclic compounds of the formula (I) where R means hydrogen atom or methyl group; n = 1 or 2, or their pharmaceutically acceptable salts that are useful as agents for treatment or prophylaxis of psychotic disorders and disorders associated with intellect deterioration. EFFECT: improved method of synthesis, valuable pharmacological properties of compounds. 13 cl, 5 ex
Title |
Year |
Author |
Number |
CARBAMIC ACID AZABICYCLIC ESTERS, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND INTERMEDIATE COMPOUNDS |
1997 |
|
RU2172739C2 |
SPIROAZOBICYCLIC HETEROCYCLIC COMPOUNDS, METHODS OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS AND PHARMACEUTICAL COMPOSITION |
1998 |
- Fillips Ehjfion
- Mehk Robert
- Mehjkor Dzhon
- Semas Sajmon
|
RU2202553C2 |
OPTICALLY PURE Na, Mg, Li, K OR Ca SALTS OF (-)-5-METHOXY-2-[[(4- -METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL]SULFINYL]-1H-BENZ-IMIDAZOLE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON SAID AND INTERMEDIATE COMPOUND |
1994 |
- Per Lennart Lindberg
- Sverker Von Unge
|
RU2137766C1 |
NOVEL COMPOUNDS |
1997 |
- Amin Kosrat
- Dakhl'Strem Mikaehl'
- Nordberg Peter
- Starke Ingemar
|
RU2184113C2 |
4-AMINO-3-ACYLQUINOLINE DERIVATIVES, METHOD OF PREPARATION THEREOF, PHARMACEUTICAL AGENT BASED THEREOF, METHOD OF PREPARATION OF PHARMACEUTICAL AGENT, AND INTERMEDIATE COMPOUND |
1994 |
|
RU2142454C1 |
PHENYLETHYL- AND PHENYLPROPYLAMINE COMPOUNDS, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL PREPARATION |
1994 |
- Stefan Bengtsson
- Sven Khell'Berg
- Nina Mokhell'
- Lian Zhang
- Gerd Khall'Nemo
- Dejvid Dzhekson
- Bengt Ul'Ff
|
RU2133735C1 |
DERIVATIVES OF (1-PHENYL-1-HETEROCYCLYL)ALKANE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL PREPARATION SHOWING NEUROPROTECTIVE EFFECT IN BRAIN ISCHEMIA, METHOD OF TREATMENT OF PATIENTS WITH HYPOXIC AND ASPHYXIC BRAIN DAMAGES |
1994 |
- Bernard Robin Bor
- Alan Dzhon Kross
- Dunkan Ehlester Grej
- Alfred Richard Grin
|
RU2137763C1 |
BICYCLIC DERIVATIVES OF ISOTHIOUREA, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
1996 |
|
RU2157802C2 |
DERIVATIVES OF OXAZOLYL- OR THIAZOLYLMETHANOL, METHODS OF THEIR SYNTHESIS (VARIANTS), PHARMACEUTICAL PREPARATION AND METHOD OF TREATMENT OF PATIENTS WITH NEURODEGENERATIVE DISORDERS |
1994 |
- Bernard Robin Bor
- Alan Dzhon Kross
- Dunkan Ehlester Grej
- Alfred Richard Grin
|
RU2139863C1 |
METHOD OF OPTICAL PURIFICATION OF ENANTIMER-ENRICHED BENZIMIDAZOLE DERIVATIVES |
1996 |
|
RU2144031C1 |