METHOD OF PREPARING 2-(4-HYDROXYPHENYL)ETHANOL Russian patent published in 2000 - IPC

Abstract RU 2151137 C1

FIELD: medicine, preparation of 2-(4-hydroxyphenyl)ethanol (n- tyrosol). SUBSTANCE: in order to prepare 2-4- (hydroxyphenyl)ethanol, 4-bromophenol is made to react with butyl lithium in ether or tetrahydrofuran at 33-34 C for 3-5 hours and then with ethylene oxide at -15- -12 C for 1 hour and at room temperature for 1 hour followed by treatment of reaction mixture with 5-20 wt % of hydrochloric acid solution in water. Yield of desired 2- (4-hydroxyphenyl)ethanol is increased to 80%. EFFECT: more efficient preparation method. 5 cl, 4 ex

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RU 2 151 137 C1

Authors

Trofimov B.A.

Tarasova O.A.

Shmidt E.Ju.

Mikhaleva A.I.

Dates

2000-06-20—Published

1998-07-20—Filed