STRAINS OF CULTURED MURINE HYBRIDOMA AS PRODUCERS OF MONOCLONAL ANTIBODIES RAISED TO HUMAN ERYTHTROPOIETIN AND ANTIBODIES PRODUCING BY THEREOF Russian patent published in 2000 - IPC

Abstract RU 2151184 C1

FIELD: biotechnology. SUBSTANCE: invention relates to hybridomas producing. Hybridomas are prepared by fusion of lymphocytes obtained from mice immunized with human erythropoietin with myeloma. Hybridomas are deposited at N VSKK/P/634D, VSKK/P/635D, VSKK/P/636D and they produce monoclonal antibodies raised to human erythropoietin. Molecular mass of monoclonal antibodies is 160 kDa and they belong to IgG1 with light chains of κ type. Invention ensures to obtain hybridoma panels producing antibodies to independent antigenic determinants of human natural erythropoietin. EFFECT: hybridoma strains indicated above, production of antibodies. 7 cl, 2 dwg, 1 tbl

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RU 2 151 184 C1

Authors

Beljakov N.V.

Korobitsyn L.P.

Pivovarov A.M.

Prokop'Ev A.A.

Sineva S.A.

Dates

2000-06-20—Published

1998-12-09—Filed