FIELD: medicine, pharmacy. SUBSTANCE: composition has the following components, wt. %: N-(hydroxymethyl)-nicotineamide ("Nikodin"), 81.0-96.4; starch, 3.0-15.0; stearic acid, 0.3-1.0; and talc, 0.3-3.0. Composition can be made as tablet. Method of preparing the composition involves the following stages: wetting active substance with starch paste, wet granulation, drying, dry granulation, powdering and formation of granules. Powdering agent is a mixture of starch with stearic acid and talc. Mass ratio of powdering agent : dry granulate = 1:(4.4-30.0). Preferable mass ratio in powdering mixture starch : stearic acid : talc = (4.8-13.0) : (0.33-1.33) : 1. Invention ensures to obtain required therapeutic concentration of active substance in body after the drug intake. Useful life of medicinal form is up to 3 years. Invention can be used for treatment of patients with cholecystitis, urinary way infections and gastroenteritis. EFFECT: high content of active substance, stability in storage, good strength of composition. 4 cl, 1 tbl, 3 ex
