FIELD: medicine. SUBSTANCE: described are new propiophenone derivatives of formula I: 
wherein OX is hydroxy group which is optionally protected; Y is lower alkyl group, and Z is β-Д glucopyranosyl group in which one or more hydroxy groups are optionally protected, or pharmaceutically acceptable salt of propiophenone. Said compounds have superb hypoglycemic activity and are therefore useful for prophylaxis or treatment of diabetes. Also described are methods of preparation thereof. EFFECT: improved properties of the title compounds. 21 cl, 22 ex, 10 tbl
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