FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes substituted 6H-1,3,4-thiadiazine-2-amines of the following general formula: 
where Ar is phenyl that can be substituted with one or more chlorine, bromine atoms, C1-C4-alkoxy- or C1-C4-alkyl-groups and where 
means morpholine, thiomorpholine, piperidine, pyrrolidine or hexamethyleneimine moiety, or their pharmaceutically acceptable salts. Invention relates to also use of these compounds as cardiovascular or hypometabolic agents and pharmaceutical compositions containing thereof. EFFECT: valuable medicinal properties of compounds, broadened arsenal of agents of indicated designation. 10 cl, 3 tbl, 18 ex
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RU2456284C1 |
| 2-PIPERIDINO-5-(THIENYL-2)- AND 2-PIPERIDINO-5-(THIENYL-3)- 6H-1,3,4-THIADIAZINES HYDROBROMIDES POSSESSING ANTIAGGREGANT ACTION | 2010 |
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