RECOMBINANT PROTEIN-FACTOR OF INHIBITION OF LIPOGENESIS, DNA ENCODING THEREOF, EXPRESSION VECTOR, RECOMBINANT MAMMALIAN STRAIN OF CELLS COS-1 AS PRODUCER OF LIPOGENESIS INHIBITORY FACTOR, METHOD OF ITS PRODUCING AND COMPOSITION SHOWING ACTIVITY OF LIPOGENESIS INHIBITION Russian patent published in 2000 - IPC

Abstract RU 2158307 C2

FIELD: molecular biology, biotechnology. SUBSTANCE: invention relates to recombinant protein-factor of inhibition of lipogenesis with molecular mass 23 kDa and DNA fragment nucleotide sequence encoding the obtained protein. Protein is produced by culturing mammalian cells COS-1 transformed with expression vector pSR-α-20-2 containing the known DNA fragment. Recombinant protein is used in composition showing the ability to inhibit lipogenesis. Invention provides the ability to carry out therapy and diagnosis of different cytopenias. EFFECT: protein-factor and DNA indicated above, valuable medicinal properties. 10 cl, 3 dwg, 9 tbl, 11 ex

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RU 2 158 307 C2

Authors

Itiro Kavasima

Dzan Okhsumi

Kendzi Mijadaj

Jo Takiguti

Dates

2000-10-27Published

1991-11-07Filed