(R)-(METHYLAMINOSULFONYLMETHYL)-3-(N-METHYLPYRROLIDINE-2-YL- -METHYL)-1H-INDOLE FUMARATE, METHOD OF ITS PREPARING, AGENT FOR TREATMENT OF MIRGAINE, PHARMACEUTICAL COMPOSITION FOR MIGRAINE TREATMENT Russian patent published in 2001 - IPC

Abstract RU 2161618 C2

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to (R)-(methylaminosulfonylmethyl)-3-(N-methyl- pyrrolidine-2-ylmethyl)-1H-indole fumarate of the formula (I) . The end product is prepared by interaction of compound (I) with fumaric acid. Compound (I) fumarate can be used in pharmaceutical composition for migraine treatment. Compound (I) fumarate is resistant to oxidative decomposition, shows excellent solubility, resistance in the solid state and absence of hygroscopicity. EFFECT: improved method of preparing, valuable physical properties. 5 cl, 3 tbl, 1 dwg

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RU 2 161 618 C2

Authors

Martin Dzhejms Uites

Dates

2001-01-10—Published

1996-04-10—Filed