FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes novel compounds of the formula (I) 
where R is given in the invention claim; R1 means H, A; R2 means OH, OA; R3 means A-CO, Ar-CO, Het-CO, Ar-O-CO, Ar-SO2 where A means alkyl with 1-6 C-atoms; Ar and Het are described in the invention claim. Compounds show antagonistic activity with respect to adhesion and GP IIb/IIIa receptors. Invention describes also methods of synthesis of indicated compounds and pharmaceutical composition based on thereof. Invention can be used in medicine for drugs preparing. EFFECT: new compounds indicated above, valuable pharmacological properties. 8 cl, 1 tbl, 40 ex
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Year |
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Number |
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1996 |
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|
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1998 |
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