DERIVATIVES OF OXAZOLIDINE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION Russian patent published in 2000 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes the novel derivatives of oxazolidine of the general formula (I) where R¹ means ; X means O; Y means piperazine residue substituted with R²; B means H, A, A-C_kH_2k or amidino-group; R² means -C_rH_2k-COOR³; R³ means H, A or benzyl; A means alkyl with 1-6 C-atoms; Ar means phenyl; k means 0, 1, 2, 3 or 4; m means 0; r means 0, 1 or 2 and their physiologically salts also. Compounds show antitumor activity and can be used as antibacterial biologically active substances also and show properties of inhibitors of fibrinogen binding. Invention describes method of their synthesis and pharmaceutical composition based on compounds of the formula (I). EFFECT: new compounds indicated above, valuable curative properties. 5 cl, 9 ex