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2 165 256

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Application

97122020/14, 1997-12-26

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Start date

1997-12-26

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Actual filing date

1997-12-26

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Published

2001-04-20

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Inventor

Kots A.Ja.Khropov Ju.V.Grafov M.A.Kulikov A.S.Ovchinnikov I.V.Belushkina N.N.Busygina O.G.Gavrilova S.A.Makhova N.N.Medvedeva N.A.Bulargina T.V.Severina I.S.

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Holder

Biologicheskij Fakul'Tet Moskovskogo Gosudarstvennogo Universiteta Im. M.V. Lomonosova

1,2,5-OXADIAZOLO[3,4-D]PYRIDAZINE-5,6-DIOXIDE DERIVATIVES AS ACTIVATORS OF SOLUBLE FORM OF GUANYLATE-CYCLASE AND AGENTS ACTIVE IN TREATMENT OF CENTRAL NERVOUS SYSTEM, AND COMPOSITIONS BASED ON THESE COMPOUNDS Russian patent published in 2001 - IPC

Abstract RU 2165256 C2

FIELD: pharmaceutical chemistry. SUBSTANCE: invention provides compounds of general formula I: (I), in which R is methyl or phenyl and n=0 or 1, as vasodilator, hypotensive, spasmolytic, antianginal agents and blood platelet aggregation inhibitors, activities of which are determined by their activating soluble form of guanylate-cyclase. EFFECT: enlarged assortment of drugs. 3 cl, 4 dwg, 4 tbl, 16 ex

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RU 2 165 256 C2

Authors

Kots A.Ja.

Khropov Ju.V.

Grafov M.A.

Kulikov A.S.

Ovchinnikov I.V.

Belushkina N.N.

Busygina O.G.

Gavrilova S.A.

Makhova N.N.

Medvedeva N.A.

Bulargina T.V.

Severina I.S.

Dates

2001-04-20—Published

1997-12-26—Filed

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