Patenton — panteon of patents

(19)

RU

(11)

2 212 409

(13)

C1

(51)

IPC

(21) (22)

Application

2001134732/04, 2001-12-24

(24)

Start date

2001-12-24

(22)

Actual filing date

2001-12-24

(45)

Published

2003-09-20

(72)

Inventor

Pirogov S.V.Kots A.Ja.Mel'Nikova S.F.Postnikov A.B.Betin V.L.Shmal'Gauzen E.V.Khropov Ju.V.Muronets V.I.Tselinskij I.V.Bulargina T.V.

(73)

Holder

Biologicheskij Fakul'Tet Moskovskogo Gosudarstvennogo Universiteta Im. M.V. Lomonosova

DERIVATIVES OF 1,4,2,5-DIOXADIAZINE Russian patent published in 2003 - IPC

Abstract RU 2212409 C1

FIELD: organic chemistry, biochemistry. SUBSTANCE: invention relates to novel chemical compounds, in part, to derivatives of 1,4,2,5-dioxadiazine of the general formula (I) wherein R means the formula (II) and R1 means N3 or NO2. These derivatives of 1,4,2,5-dioxadiazine are activators of soluble form of guanylate cyclase. Invention provides the development of novel activators of soluble form of guanylate cyclase. EFFECT: valuable biochemical properties of compounds. 2 cl, 1 tbl

Similar patents RU2212409C1

Title Year Author Number
DONOR OF NITROGEN OXIDE ACTIVATING SOLUBLE FORM OF GUANYLATE CYCLASE, INHIBITING PLATELET AGGREGATION AND EXHIBITING SPASMOLYTIC AND VASODILATING EFFECT 2001
  • Mel'Nikova S.F.
  • Kots A.Ja.
  • Pirogov S.V.
  • Postnikov A.B.
  • Betin V.L.
  • Pjatakova N.V.
  • Grafov M.A.
  • Gavrilova S.A.
  • Seliverstov V.O.
  • Khropov Ju.V.
  • Medvedeva N.A.
  • Severina I.S.
  • Tselinskij I.V.
  • Bulargina T.V.
 RU2208438C1
INHIBITOR OF NO-DEPENDENT ACTIVATION OF SOLUBLE FORM OF GUANYLATE CYCLASE 2001
  • Khropov Ju.V.
  • Pjatakova N.V.
  • Gavrilova S.A.
  • Busygina O.G.
  • Krasnoperov R.A.
  • Medvedeva N.A.
  • Severina I.S.
 RU2189392C1
1,2,5-OXADIAZOLO[3,4-D]PYRIDAZINE-5,6-DIOXIDE DERIVATIVES AS ACTIVATORS OF SOLUBLE FORM OF GUANYLATE-CYCLASE AND AGENTS ACTIVE IN TREATMENT OF CENTRAL NERVOUS SYSTEM, AND COMPOSITIONS BASED ON THESE COMPOUNDS 1997
  • Kots A.Ja.
  • Khropov Ju.V.
  • Grafov M.A.
  • Kulikov A.S.
  • Ovchinnikov I.V.
  • Belushkina N.N.
  • Busygina O.G.
  • Gavrilova S.A.
  • Makhova N.N.
  • Medvedeva N.A.
  • Bulargina T.V.
  • Severina I.S.
 RU2165256C2
INCLUSION COMPLEXES OF DERIVATIVES OF 1,2,5-OXA- -DIAZOLE-2-OXIDE WITH POLYCYCLIC DERIVATIVES OF GLUCOPYRANOSE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION 2001
  • Khropov Ju.V.
  • Kots A.Ja.
  • Postnikov A.B.
  • Bogdanova N.G.
  • Gavrilova S.A.
  • Grafov M.A.
  • Volchkova I.L.
  • Pjatakova N.V.
  • Betin V.L.
  • Kulikov A.S.
  • Ovchinnikov I.V.
  • Zapesochnaja G.G.
  • Matveenko V.N.
  • Makhova N.N.
  • Medvedeva N.A.
  • Severina I.S.
  • Bulargina T.V.
 RU2186782C1
INHIBITOR OF NO-DEPENDENT ACTIVATION OF GUANYLATE CYCLASE SOLUBLE FORM 2001
  • Pjatakova N.V.
  • Khropov Ju.V.
  • Busygina O.G.
  • Severina I.S.
  • Preobrazhenskaja M.N.
 RU2188865C1
DONOR OF NITROGEN OXIDE AND ACTIVATOR OF SOLUBLE FORM OF GUANYLATE CYCLASE 1998
  • Pirogov S.V.
  • Khropov Ju.V.
  • Kots A.Ja.
  • Ukraintsev K.Eh.
  • Grafov M.A.
  • Davydova M.P.
  • Mel'Nikova S.F.
  • Medvedeva N.A.
  • Tselinskij I.V.
  • Bulargina T.V.
 RU2139932C1
SPECIFIC REGULATOR OF ACTIVITY OF NUCLEOTIDE-DEPENDENT ENZYMES 1997
  • Kots A.Ja.
  • Kulikov A.S.
  • Khropov Ju.V.
  • Ovchinnikov I.V.
  • Belushkina N.N.
  • Busygina O.G.
  • Shmal'Gauzen E.V.
  • Jazykova M.Ju.
  • Mast N.V.
  • Jakimova N.G.
  • Lopina O.D.
  • Makhova N.N.
  • Bulargina T.V.
  • Muronets V.I.
  • Severina I.S.
 RU2130490C1
DONOR OF NITROGEN OXIDE AND ACTIVATOR OF GUANYLATE CYCLASE SOLUBLE FORM 1997
  • Ovchinnikov I.V.
  • Khropov Ju.V.
  • Busygina O.G.
  • Kots A.Ja.
  • Ukraintsev K.Eh.
  • Makhova N.N.
  • Bulargina T.V.
  • Severina I.S.
 RU2123046C1
INHIBITOR OF GUANYLATE CYCLASE SOLUBLE FORM 1999
  • Kots A.Ja.
  • Batog L.V.
  • Betin V.L.
  • Rozhkov V.Ju.
  • Ukraintsev K.Eh.
  • Khropov Ju.V.
  • Epishina M.A.
  • Sheremetev A.B.
  • Makhova N.N.
  • Bulargina T.V.
 RU2151799C1
INHIBITOR OF GUANYLATE CYCLASE SOLUBLE FORM 2001
  • Betin V.L.
  • Bakhmedova A.A.
  • Gorjunova O.V.
  • Miniker T.D.
  • Plikhtjak I.L.
  • Ehktova L.V.
  • Postnikov A.B.
  • Khropov Ju.V.
  • Kots A.Ja.
  • Mel'Nik S.Ja.
  • Bulargina T.V.
 RU2196175C2

RU 2 212 409 C1

Authors

Pirogov S.V.

Kots A.Ja.

Mel'Nikova S.F.

Postnikov A.B.

Betin V.L.

Shmal'Gauzen E.V.

Khropov Ju.V.

Muronets V.I.

Tselinskij I.V.

Bulargina T.V.

Dates

2003-09-20—Published

2001-12-24—Filed

download Download PDF read Similar patents