NITROCOMPOUNDS AND PHARMACEUTICAL COMPOSITION SHOWING ANTI-INFLAMMATORY AND ANTITHROMBOTIC ACTIVITY Russian patent published in 2001 - IPC

Abstract RU 2165921 C2

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes novel compounds or their compositions of the general formula A-X1-NO2 or their salts that can be used as drugs where A means R-(COX)t or 1; X means O; R means (a) where means -CH2-ONO2,-CH2CH2CH2CH2,-CH2CH2ONO2 where Xo-X,R1 means OCOR3-group where R3 means methyl; R2 means hydrogen atom, nitro-group; X1 in formula A1-X1-NO2 means bivalent connective bridge taken among the following ones: -YO where Y is taken among linear or if it is admissible among branched C1-C20-alkylene, -(CH2-CH(R2a)-O)n-(YO)r- where n means whole number from 1 to 6; R2a means H, CH3; r = 1; Y is CH2-CH2. New compounds show anti-inflammatory, analgetic and antithrombotic activities. EFFECT: new compounds indicated above, valuable medicinal properties. 3 cl, 1 tbl

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RU 2 165 921 C2

Authors

Del Soldato P'Ero

Sannikolo Franchesko

Dates

2001-04-27Published

1996-10-29Filed