FIELD: medicine. SUBSTANCE: method involves applying retrovirus protease inhibitor combinations showing retrovirus replication inhibition activity in vitro or in vivo. Protease inhibitor compounds are also useable in combined therapy with other protease inhibitor compounds and in combined therapy with antiviral preparations different from protease inhibitors. EFFECT: prevented cultivation of retrovirus strains resistant to retrovirus protease inhibitors. 20 dwg, 11 tbl
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