FIELD: medicine. SUBSTANCE: described is method of preparing piperazinyl pentaneamide derivatives of general formula: 
wherein R1 is C1-C4 alkyl, unsubstituted or substituted by one or more groups selected from (1) aryl unsubstituted or substituted by one or more groups selected from C1-C4 alkyl, hydroxy or aryl wherein aryl is phenyl or naphtyl; (2) heterocycle unsubstituted or substituted by one or more groups selected form C1-C4 alkyl or butyloxy carbonyl wherein heterocycle is 5-6 membered saturated or unsaturated heterocyclic ring system optionally condensed with benzene ring containing as heteroatoms, one or two nitrogen atoms or nitrogen, or nitrogen and oxygen. Compound of formula (i)
is reacted with compound of formula: R1-X wherein X is selected from Cl, Br or I. Method makes it possible to prepare new compounds of formula I which are useful for prophylaxis or treatment of HIDV infection or for treating AIDS in the form of compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, irrespective of the fact whether they are or not combined with other antiviral agents, immune modulators, antibiotics or vaccines. Also described are intermediate compounds (i) for preparing compounds I. EFFECT: improved properties of the title compounds. 7 cl, 1 dwg, 18 ex, 1 tbl
