FIELD: medicine, virology. SUBSTANCE: invention relates to method involving administration in needing patient the compound N-(2(R)-hydroxy-1(S)-indanyl)-2(R)-phenylmethyl-4(S)-hydroxy-5-(1-(4-(3-pyridylmethyl)-2(S)-N'-(tert. -butylcarbamoyl)-piperazinyl))pentane-amide (component A) or its pharmaceutically acceptable alt in combination with (component B) or its pharmaceutically acceptable salt. The proposed method ensures to enhanced effectiveness of treatment due to adverse effects. Invention can be used for inhibition of activity of HIV-proteases, prophylaxis and treatment of HIV-infection or treatment of patients with AIDS. EFFECT: enhanced effectiveness of treatment. 7 cl, 4 tbl
Authors
Dates
2002-12-20—Published
1995-08-07—Filed