DIOL-CONTAINING QUINOLINE DERIVATIVES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL PREPARATION BASED ON THEREOF AND METHOD OF INHIBITION Russian patent published in 2001 - IPC

Abstract RU 2171803 C2

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to diol-containing derivatives of quinoline of the general formula (I) where R¹ means hydrogen or halogen atom but preferably fluorine or chlorine atom; m = 0, 1 or 2. Indicated compounds are synthesized by interaction of amine of the formula (II) with compound of the formula (III) . Compounds of the formula (I) show antagonistic activity and therefore they can be used as the pharmaceutical preparation in medicine. Invention relates to method of inhibition of specific contraction of smooth muscle also. EFFECT: improved method of synthesis, valuable medicinal properties. 8 cl, 3 tbl, 9 ex

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RU 2 171 803 C2

Authors

Rakhlin Shneur

Kirstejn Dorte

Dates

2001-08-10—Published

1996-11-13—Filed