FIELD: medicine. SUBSTANCE: described are substituted, indanylidine acetyl guanidines of formula I: 
wherein R1,R2,R3,R4,R5,R6 are hydrogen, alkyl, alkyloxy, F,Cl, Br,F: R7,R9,R9,R10 are hydrogen, and X is O. Compound of general formula I have inhibiting activity with respect to Na/H exchange and are therefore used as medicinals or diagnostic agents. Described is method of formula I by reacting compound of formula V: 
wherein Y is alkoxy, halogen or imidazolyl with guandine of formula VI 
. EFFECT: improved properties of the title compounds. 16 cl, 2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| INDENOILGUANIDINE, METHOD FOR ITS OBTAINING AND MEDICINAL PREPARATION | 1996 |
|
RU2182902C2 |
| SUBSTITUTED 1-NAPHTHOYLGUANIDINES AND MEDICINAL AGENT BASED ON THEREOF | 1997 |
|
RU2182901C2 |
| SUBSTITUTED 2-NAPHTHOYLGUANIDINES AND MEDICINAL AGENT BASED ON THEREOF | 1997 |
|
RU2190600C2 |
| BENZOYLGUANIDINES, METHOD OF THEIR SYNTHESIS, METHOD OF INHIBITION, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING | 1996 |
|
RU2165412C2 |
| ALKENYLCARBOXYLIC ACID GUANIDIDES, METHOD OF THEIR SYNTHESIS, METHOD OF INHIBITION OF CELLULAR Na/H-EXCHANGE AND PHARMACEUTICAL COMPOSITION | 1996 |
|
RU2164913C2 |
| NOVEL ARYLALKYLINDOLES SHOWING AFFINITY TO SEROTONIN RECEPTOR AND USEFUL AS DRUGS, METHOD FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF | 2003 |
|
RU2320663C2 |
| AMINOACID-SUBSTITUTED BENZOYL GUANIDINES METHOD OF PREPARATION THEREOF, METHOD OF INHIBITING CELLULAR Na/H-ION EXCHANGE, AND MEDICINAL AGENT | 1995 |
|
RU2154055C2 |
| NEW TETRACYCLIC ARYLCARBONYLINDOLS WITH AFFINITY TO SEROTONINE RECEPTORS APPLICABLE AS PHARMACEUTICALS, METHOD OF THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS ON THEIR BASE | 2003 |
|
RU2325392C2 |
| ORTHO-SUBSTITUTED BENZOYLGUANIDINES AND MEDICINAL AGENT BASED ON THEREOF | 1997 |
|
RU2193025C2 |
| BENZOYLGUANIDINES, METHOD OF PREPARATION THEREOF, INTERMEDIATES FOR THEIR PREPARATION, INHIBITION METHOD, AND DRUG | 1995 |
|
RU2160727C2 |
