FIELD: medicine. SUBSTANCE: described are new aminoacid-substituted benzoyl guantidines of general formula I: 
wherein R(1)-R(5) are as defined in claim 1. Compound of formula I is useful is preparing medicinal agent for treatment of heart blood circulation. Also described are method of preparation thereof, method of inhibiting cellular Na+/H+ ion exchange, and medicinal agent. EFFECT: improved properties of the medicinal agent. 9 cl, 8 ex
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