TRICYCLIC DERIVATIVES OF PYRAZOLE, PHARMACEUTICAL COMPOSITION Russian patent published in 2002 - IPC

FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention describes a tricyclic derivative of pyrazole of the general formula (I) or its pharmaceutically acceptable salt where Het means 5-membered unsaturated heterocyclic ring comprising a heteroatom taken among a group consisting of sulfur atom or oxygen atom or Het means isoxazole; A means a linear or branched lower alkylene group; R means hydrogen atom, lower alkyl group, halogen atom or lower alkoxy-group. Compounds show high affinity and selectivity with respect to 5-HT_2C-receptor and useful for treatment of diseases of the central nervous system (for example, sexual disorders, appetite disorder, fear, depression, sleep disorders and so on). EFFECT: valuable medicinal properties of compounds. 4 cl, 4 tbl