FIELD: medicine. SUBSTANCE: method involves cleaning implant surface and applying coating layer. Coating is produced by applying microacrch oxidation in the presence of biologically active agent(s) forming the biologically active coating. The implant is manufactured from a metal to be selected from a group including titanium, aluminum, zirconium. Hydroxyapatite is used as biologically active agent. EFFECT: production of implants showing biological activity. 4 cl, 3 dwg, 1 tbl
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