INHIBITION OF PROTEASOMES WITH 26S- AND 20S-INDANONES Russian patent published in 2002 - IPC

Abstract RU 2195310 C2

FIELD: organic chemistry, medicine. SUBSTANCE: invention proposes method of treatment of mammals with damages of cellular proliferation, disorders of immune system and infectious diseases that involves administration of therapeutically effective amount of compound of the formula (I) . Invention proposes also compositions based on thereof. Method does not cause unfavorable toxicological effects but shows effectiveness in disorders associated with accelerated cellular proliferation. EFFECT: enhanced method of treatment. 39 cl, 2 tbl, 3 dwg, 5 ex

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RU 2 195 310 C2

Authors

Lum Robert T.

Skou Stiven R.

Dzholi Ehlison

Kervor Suresh

Nel'Son Marek Dzh.

Vik Majkl M.

Dates

2002-12-27Published

1997-09-23Filed