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2 205 183

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IPC

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Application

97101899/04, 1995-07-04

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Start date

1995-07-04

(22)

Actual filing date

1995-07-04

(45)

Published

2003-05-27

(72)

Inventor

Blan VeronikTibo DeniBama-Zhak NataliBlansh FransisKruze Zhoehl'Bar'Er Zhan-KlodDebjussh LoranFameshon AlanPari Zhan-MarkDjutrjuk-Rosse Zhill'

(73)

Holder

Ron-Pulenk Rore S.A.

NOVEL STREPTOGRAMINS, METHOD FOR THEIR PREPARING, NUCLEOTIDE SEQUENCES, POLYPEPTIDES AND PHARMACEUTICAL COMPOSITION Russian patent published in 2003 - IPC

Abstract RU 2205183 C2

FIELD: biotechnology, antibiotics, pharmacy. SUBSTANCE: invention relates to novel streptogramins of the formula (I) and to method for preparing streptogramins by mutasynthesis using a mutated microorganism for alternation of biosynthesis of at least a single precursor of streptogramins. Invention describes also nucleotide sequences and polypeptides taking part in biosynthesis of these precursors. Invention describes also pharmaceutical composition based on the claimed compounds and eliciting an antibacterial activity. EFFECT: improved preparing method, valuable medicinal properties of compounds. 40 cl, 13 dwg, 5 tbl

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RU 2 205 183 C2

Authors

Blan Veronik

Tibo Deni

Bama-Zhak Natali

Blansh Fransis

Kruze Zhoehl'

Bar'Er Zhan-Klod

Debjussh Loran

Fameshon Alan

Pari Zhan-Mark

Djutrjuk-Rosse Zhill'

Dates

2003-05-27—Published

1995-07-04—Filed